Sep 24, 2026

6 Everyday Medications That Are Up To 94% Cheaper at Costco Than CVS

Written by Gabrielle Olya
|
Edited by Zuri Anderson
6 Everyday Medications That Are Up To 94% Cheaper at Costco Than CVS

Costco is known for bulk groceries and household essentials, but some of the warehouse club's biggest savings may be hiding in the pharmacy aisle.

A comparison of over-the-counter medication prices found that several common drugs cost dramatically less at Costco than comparable options at CVS, in some cases by more than 90%.

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Here are six common medications that cost significantly less at Costco.

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Costco: Kirkland Signature Extra Strength Acetaminophen

  • Price: $9.99 for 1,000 tablets

  • Cost per tablet: 1 cent

CVS: CVS Extra Strength Acetaminophen Pain Reliever & Fever Reducer

  • Price: $6.89 for 50 tablets

  • Cost per tablet: 13.8 cents

If you took two acetaminophen tablets daily, you would pay $5.83 per year at Costco compared to $100.59 a year at CVS — that's a 94% annual savings at Costco.

Costco: Kirkland Signature Ibuprofen

  • Price: $13.99 for 1,000 tablets

  • Cost per tablet: 1 cent

CVS: CVS Ibuprofen Pain Reliever & Fever Reducer

  • Price: $15.49 for 200 tablets

  • Cost per tablet: 7.7 cents

Ibuprofen users could pay less than one-seventh as much per tablet by buying Costco's store-brand version.

Costco: Claritin RediTabs (10 mg)

  • Price: $34.99 for 70 tablets

  • Cost per tablet: 50 cents

CVS: Claritin RediTabs (10 mg)

  • Price: $45.99 for 60 tablets

  • Cost per tablet: 76.7 cents

For allergy sufferers who rely on Claritin year-round, buying at Costco could save nearly $100 annually.

Costco: Benadryl Allergy UltraTabs

  • Price: $22.99 for 144 tablets

  • Cost per tablet: 16 cents

CVS: Benadryl Allergy UltraTabs

  • Price: $8.59 for 24 tablets

  • Cost per tablet: 35.8 cents

Benadryl is 55% cheaper at Costco than at CVS, so it's worth stocking up at the warehouse club before allergy season.

Costco: Pepcid Complete Dual Action Acid Reducer + Antacid

  • Price: $33.99 for 100 tablets

  • Cost per tablet: 34 cents

CVS: Pepcid Complete Dual Action Acid Reducer + Antacid

  • Price: $29.49 for 50 tablets

  • Cost per tablet: 59 cents

Heartburn sufferers can cut their cost per tablet by more than 40% when buying Pepcid at Costco.

Costco: Zyrtec 24-Hour Allergy Relief Tablets

  • Price: $41.99 for 120 tablets

  • Cost per tablet: 35 cents

CVS: Zyrtec 24-Hour Allergy Relief Tablets

  • Price: $48.49 for 90 tablets

  • Cost per tablet: 53.9 cents

Costco shoppers pay about one-third less per dose for Zyrtec than CVS customers.

Editor’s note: Prices and availability are subject to change.

This article was provided by MoneyLion.com for informational purposes only and should not be construed as financial, legal or tax advice.

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Written by
Gabrielle Olya
Edited by
Zuri Anderson